Clascoterone CAS:19608-29-8 Mea Hana Mea Hoʻolako

Ke hoʻomohala ʻia nei ʻo Clascoterone ma ke ʻano he kirīmi topical e Cassiopea no nā maʻi ʻili e pili ana i ka androgen. ʻO Clascoterone (cortexolone 17α-propionate, CB-03-01) kahi antagonist hou o nā mea loaʻa androgen. Hoʻopaʻa ia i nā mea loaʻa androgen me ka pilina kiʻekiʻe. Ma ka hoʻokūkū ʻana me nā androgens no ka hoʻopaʻa ʻana i nā mea loaʻa androgen, hana ʻo clascoterone ma ke kāohi ʻana i nā cascades hōʻailona androgen receptor e hoʻolaha ana i ka pathogenesis acne, e like me ka hoʻonui ʻia ʻana o ke kelepa sebaceous, ka hana sebum keu, a me nā ala mumū. I ʻAukake 2020, ua ʻāpono ka FDA i ka clascoterone no ka mālama ʻana i ka ʻeha (acne vulgaris) i nā maʻi kāne a me nā wahine he 12 mau makahiki a ʻoi. Ke noiʻi ʻia nei hoʻi ʻo Clascoterone ma ke ʻano he lāʻau hou no ka androgenetic alopecia.