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ʻO ka mea hoʻohuihui CAS:439239-90-4
ʻO Lasmiditan, i kūʻai ʻia ma lalo o ka inoa inoa ʻo Reyvow, he hui lāʻau lapaʻau hou i hoʻolālā ʻia e hōʻoluʻolu i nā hoʻouka migraine koʻikoʻi i nā pākeke. No ka papa o nā agonists receptor serotonin koho, e kuhikuhi pono ana i ka subtype receptor 5-HT1F. ʻO kēia ʻano hana e hoʻokaʻawale iā Lasmiditan mai nā lāʻau migraine kuʻuna, ʻoiai ʻaʻole ia e hoʻoulu i ka vasoconstriction, e kūpono ai no nā poʻe maʻi me nā mea pilikia cardiovascular.
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N-Methylcarbonyl-2-chloroacetamidrazone CAS:155742-64-6
ʻO N-Methylcarbonyl-2-chloroacetamidrazone kahi hui kemika i ʻike ʻia no kāna mau hoʻohana like ʻole i ka synthesis organik a me ka kemika hoʻonohonoho. ʻO kāna synthesis e pili ana i ka hopena o N-methylcarbamoyl chloride me 2-chloroacetohydrazide, e hopena ana i kahi hui me nā waiwai kūkulu a me nā hana like ʻole. Hōʻike ʻia kēia hui e kona hiki ke hana i nā hui me nā ion metala like ʻole, e lilo ia i mea waiwai nui i nā haʻawina kemika hoʻonohonoho. Eia kekahi, ʻo kāna mau hui carbonyl a me amidrazone e hāʻawi i kāna reactivity a me nā hana pharmacological hiki, ʻo ia nā wahi o ka hoihoi noiʻi e hoʻomau nei.
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ʻO Lasmiditan HCl CAS:613677-28-4
ʻO Lasmiditan hydrochloride (Lasmiditan HCl) kahi hui lāʻau lapaʻau i kaulana no kāna kuleana i ka mālama ʻana i nā hoʻouka migraine koʻikoʻi i nā pākeke. Hoʻomohala ʻia ma ke ʻano he agonist receptor serotonin koho, e kuhikuhi pono ana i ka subtype receptor 5-HT1F, hōʻike ʻo Lasmiditan HCl i kahi holomua koʻikoʻi i ka mālama ʻana i ka migraine ma muli o kāna ʻano hana kū hoʻokahi a me ka pono lapaʻau.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS:613678-03-8
ʻO (6-Aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone, i ʻike ʻia hoʻi ʻo aminopyridine methylpiperidone, he hui kemika me nā hopena koʻikoʻi i ka kemika lāʻau lapaʻau a me ka noiʻi lāʻau lapaʻau. Hoʻohui ʻia ma o ka hopena o ka waikawa 6-aminopicolinic me 1-methylpiperidin-4-one, hōʻike kēia hui i nā hiʻohiʻona kūkulu kūikawā e hāʻawi i kona hiki pharmacological a me ka versatility hana.
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(S)-(+)-3-Quinuclidinol CAS:34583-34-1
ʻO (S)-(+)-3-Quinuclidinol, i ʻike wale ʻia ʻo quinuclidinol, he hui koʻikoʻi ia i ka kemika organik a me ka noiʻi lāʻau lapaʻau ma muli o kona ʻano kū hoʻokahi a me nā noi like ʻole. Loaʻa kēia hui chiral mai ka quinuclidine a hōʻike i nā waiwai kemika a me nā pharmacological ʻokoʻa i huki i ka manaʻo ma nā ʻano ʻepekema like ʻole.
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Nā Waena APREPITANT CAS:171482-05-6
He kuleana koʻikoʻi ko nā mea waena o Aprepitant i ka synthesis lāʻau lapaʻau o ka aprepitant, kahi antagonist receptor neurokinin-1 (NK1) ikaika i hoʻohana nui ʻia i ka pale ʻana i ka nausea a me ka luaʻi i hoʻokomo ʻia e ka chemotherapy (CINV). He mau mea koʻikoʻi kēia mau mea waena i ke ala synthetic multi-step e alakaʻi ana i ka hoʻopili hope loa o ka aprepitant. Ua ʻike ʻia ʻo Aprepitant no kona pono i ka hoʻokele ʻana i ka CINV, e hāʻawi ana i ka hōʻoluʻolu nui i nā poʻe maʻi e hana ana i ka chemotherapy. Pili ka synthesis o aprepitant i kekahi mau ʻanuʻu koʻikoʻi, me nā mea waena e lawelawe ana ma ke ʻano he mau poloka hale e hiki ai ke hana pono i kēia mea lapaʻau koʻikoʻi.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS:79538-29-7
ʻO 2,4,6-Trifluorobenzoyl chloride, i ʻike ʻia hoʻi ʻo trifluorobenzoyl chloride, he hui kemika koʻikoʻi i mahalo ʻia no kāna mau noi like ʻole i ka synthesis organik a me nā kaʻina hana ʻoihana. Hoʻohui ʻia ma o ka chlorination o ka 2,4,6-trifluorobenzoic acid, hōʻike kēia hui i nā waiwai kemika kūikawā e kōkua i kona hoʻohana ākea ʻana ma nā ʻano like ʻole.
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4-Chloro-6-iodoquinazoline CAS:98556-31-1
ʻO 4-Chloro-6-iodoquinazoline kahi hui kemika me ke ʻano molekala C9H5ClIN2. Hōʻike ʻia ia e ke alo o nā ʻātoma chlorine a me iodine i hoʻopili ʻia i kahi ʻano apo quinazoline. Hoʻohana nui ʻia kēia hui i ka noiʻi lāʻau lapaʻau a me ka synthesis organik ma muli o kāna mau noi hiki ke hoʻomohala i nā lāʻau hou a me nā molekala biologically active ʻē aʻe.
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(R)-3-Quinuclinol CAS:25333-42-0
ʻO (R)-3-Quinuclinol, i ʻike ʻia hoʻi ʻo quinuclidinol, he hui koʻikoʻi ia i ka kemika organik a me ka noiʻi lāʻau lapaʻau ma muli o kona ʻano kū hoʻokahi a me nā hoʻohana like ʻole. Loaʻa kēia hui chiral mai ka quinuclidine a hōʻike i nā waiwai kemika a me nā pharmacological ʻokoʻa i huki i ka manaʻo ma nā ʻano ʻepekema like ʻole.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
ʻO ka hui (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate he molekole organik paʻakikī me nā ʻano kūkulu a me nā ʻano pharmacological kikoʻī. No ka papa morpholine o nā hui, i hoʻohana pinepine ʻia i ka kemika lāʻau lapaʻau ma muli o kā lākou mau hana olaola like ʻole.
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![ʻO (S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
ʻO (S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0
ʻO (S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine kahi hui kemika i ʻike ʻia no kāna mau hoʻohana like ʻole i ka synthesis organik a me ka kemika lāʻau lapaʻau. Hoʻohui ʻia ma o ka hopena o (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone me ka ammonia a i ʻole ka amine, loaʻa i kēia hui nā hiʻohiʻona ʻokoʻa e hāʻawi i kona ʻokoʻa hana a me nā hana pharmacological hiki.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS:608142-27-4
ʻO (R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine kahi hui kemika i ʻike ʻia no kāna mau noi like ʻole i ka synthesis organik a me ke kemika lāʻau lapaʻau. Hoʻohui ʻia ma o ka hopena o 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone me ka ammonia a i ʻole ka amine, hōʻike kēia hui i nā hiʻohiʻona kūkulu kūikawā e hāʻawi i kona versatility hana a me nā hana pharmacological hiki.
