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N-(2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl-urea CAS:796848-79-8
N-ʻO (2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl-urea kahi hui kemika me ke ʻano molekala C10H11ClN2O2. No ka papa o nā derivatives urea i pani ʻia me kahi hui chloro-hydroxyphenyl a me kahi hui cyclopropyl. Ua ʻike ʻia kēia hui no kona paʻakikī kūkulu a me nā hoʻohana hiki ke hana ʻia i nā haʻawina kemika a me nā biology like ʻole.
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1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester CAS: 205448-65-3
ʻO 1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester kahi hui kemika me ke ʻano molekala C12H11NO4. No ka papa quinoline o nā hui a ua hōʻailona ʻia e kahi hui methyl ester i hoʻopili ʻia i kahi apo quinoline, me kahi substituent methoxy ma ke kūlana 7 a me kahi hui keto ma ke kūlana 4.
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AZD-9291 mesylate CAS:1421373-66-1
He hui lāʻau lapaʻau ʻo AZD-9291 mesylate me ke ʻano molekala C28H33N7O4∙CH4O3S. No ka papa o nā mea hoʻopaʻa tyrosine kinase a hoʻohana nui ʻia i ka mālama ʻana i ka maʻi ʻaʻai māmā ʻaʻole liʻiliʻi (NSCLC). Hoʻopili koho kēia lāʻau a kāohi i nā ʻano mutated o ka epidermal growth factor receptor (EGFR), i loaʻa pinepine i nā tumors NSCLC.
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5-Chloromethyl-2H-1,2,4-triazolin-3-one CAS:252742-72-6
He hui kemika koʻikoʻi ʻo 5-Chloromethyl-2H-1,2,4-triazolin-3-one me nā hoʻohana like ʻole i ka kemika lāʻau lapaʻau a me ka noiʻi agrochemical. No ka papa o nā derivatives triazolinone, i hoʻokaʻawale ʻia e kahi ʻano molekala kū hoʻokahi e hāʻawi i kāna mau hana olaola a me nā hoʻohana therapeutic hiki.
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5-CHLOROTIOPHENE-2-CARBONYL CHLORIDE CAS:42518-98-9
ʻO 5-Chlorothiophene-2-carbonyl chloride kahi hui kemika e pili ana i ka papa o thienylacyl chlorides. Hōʻike ʻia e kona ʻano molekala i haku ʻia me kahi apo thiophene i pani ʻia me kahi hui chloro ma ke kūlana 5 a me kahi hui carbonyl chloride ma ke kūlana 2. He mea hoihoi nui kēia hui i ka synthesis organik ma muli o kona reactivity versatile a me nā noi hiki ke hoʻohana ʻia i nā lāʻau lapaʻau a me ka ʻepekema mea.
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5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone CAS:503615-03-0
ʻO 5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone kahi hui kemika i ʻike ʻia no kona ʻano molekala paʻakikī a me nā noi like ʻole i ka kemika lāʻau lapaʻau a me ka noiʻi lāʻau lapaʻau. No ka papa o pyridinones kēia hui a ua ʻokoʻa ʻia e kona hoʻonohonoho kūikawā o nā hui hana, e hāʻawi ana i nā waiwai kikoʻī koʻikoʻi no kāna mau hana olaola.
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4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester CAS:5909-24-0
ʻO 4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester kahi hui kemika i ʻike ʻia no kāna kuleana koʻikoʻi i ka kemika lāʻau lapaʻau a me ka noiʻi lāʻau lapaʻau. No ka māhele o nā pyrimidine derivatives, hōʻike kēia hui i kahi ʻano molekala kūikawā koʻikoʻi no kāna mau hana olaola a me nā noi therapeutic.
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3-CHLORO-4-METHOXYBENZYLAMINE HYDROCHLORIDE CAS:41965-95-1
ʻO 3-Chloro-4-Methoxybenzylamine Hydrochloride kahi hui kemika kaulana i ʻike nui ʻia no kāna mau noi ʻana i ka kemika lāʻau lapaʻau a me ka noiʻi lāʻau lapaʻau. Hāʻule kēia hui i loko o ka papa o nā amines ʻala a ua hoʻokaʻawale ʻia e kona hoʻonohonoho kikoʻī o nā hui hana koʻikoʻi no kāna mau hana olaola.
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3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one CAS:545445-44-1
ʻO 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one kahi hui kemika i kaulana no kona ʻano molekala paʻakikī a me nā noi like ʻole i ka kemika lāʻau lapaʻau a me ka hoʻomohala ʻana i nā lāʻau lapaʻau. No ka papa o dihydropyridinones kēia hui a ua ʻike ʻia e kona hoʻonohonoho paʻakikī o nā hui hana, e hāʻawi ana i nā waiwai kikoʻī koʻikoʻi no kāna mau hana olaola.
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ʻAkika L(-)-Thiazolidine-4-carboxylic CAS:34592-47-7
ʻO ka L(-)-Thiazolidine-4-carboxylic acid kahi hui kemika kaulana i ʻike ʻia no kāna mau hoʻohana like ʻole i ka kemika lāʻau lapaʻau a me ka noiʻi lāʻau lapaʻau. No ka papa o nā derivatives thiazolidine, loaʻa i kēia hui kahi ʻano molekala ʻokoʻa e pili ana i kāna mau hana olaola a me ka hiki ke hoʻōla.
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ʻO Nintedanib CAS:656247-17-5
He mea hoʻopaʻa tyrosine kinase molekole liʻiliʻi (TKI) ikaika ʻo Nintedanib me kahi pilina therapeutic koʻikoʻi i ka oncology a me nā maʻi fibrotic. Hoʻopuka ia i kāna mau hopena pharmacological ma o ka hoʻopaʻa ʻana i nā tyrosine kinases receptor he nui e pili ana i ka angiogenesis, fibrogenesis, a me ka hoʻoponopono ʻana i ka ulu ʻana o ka tumor.
