Ibandronate Sodium CAS:138844-81-2 Mea Hoʻolako Mea Hana

Ua hoʻohana ʻia ʻo Ibandronate sodium e aʻo i kona hopena i ka hoʻonui ʻana a me ka ultrastructure o Leishmania a me Giardia e ka hana ʻana o nā pihi kuʻuna.Ua hoʻohana pū ʻia e wehewehe i ke ala e komo ai nā bisphosphonates nitrogen-containing (N-BPs) i ka cytosol a keʻakeʻa i kā lākou molecular target.Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM).ʻO ka sodium Ibandronate kekahi mea hoʻopiʻi hoʻopiʻi iwi.Ua noiʻi ʻia no nā hopena anti-tumor in vitro, e like me ka apoptosis induction, inhibitor o ka ulu ʻana o ka cell, inhibition of invasive behavior, and inhibition of angiogenesis a no kāna hana in vivo i nā maʻi maʻi like ʻole me ka umauma a me ka maʻi prostate.