Ibandronate Sodium CAS:138844-81-2 Mea Hana Mea Hoʻolako

Ua hoʻohana ʻia ka sodium Ibandronate e aʻo i kona hopena ma ka hoʻonui ʻana a me ka ultrastructure o Leishmania lāua ʻo Giardia ma o ka hana ʻana o nā curve concentration. Ua hoʻohana ʻia hoʻi e wehewehe i ke ala e komo ai nā bisphosphonates i loaʻa ka nitrogen (N-BPs) i ka cytosol a kāohi i kā lākou pahuhopu molekala. Hoʻopilikia ka sodium Ibandronate i ka farnesyl diphosphate synthase (IC50 = 20 nM). ʻO ka sodium Ibandronate kekahi mea hoʻopaʻa i ka resorption iwi. Ua noiʻi ʻia no nā hopena anti-tumor in vitro, e like me ka apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, a me ka inhibition of angiogenesis a no kāna kuleana in vivo i nā maʻi kanesa like ʻole me nā maʻi kanesa umauma a me ka prostate.