Linezolid CAS:165800-03-3

Hoʻohana nui ʻia ʻo Linezolid i ka hana lapaʻau no ka hoʻokele ʻana i nā maʻi bacteria Gram-positive koʻikoʻi i kūʻē i nā antibiotics ʻē aʻe. Hoʻohana pinepine ʻia ia no nā maʻi ʻili a me nā ʻiʻo palupalu, ka pneumonia, ka bacteremia, a me nā maʻi iwi i hoʻokumu ʻia e MRSA, VRE, a me nā pathogens multidrug-resistant ʻē aʻe. ʻO ka hiki iā Linezolid ke kuhikuhi i kēia mau meaola paʻakikī e mālama ai e lilo ia i mea lapaʻau koʻikoʻi i ka hakakā ʻana i nā maʻi paʻakikī. Ma nā wahi haukapila, hoʻohana pinepine ʻia ʻo linezolid no ka mālama ʻana i nā maʻi nosocomial a me ka pneumonia e pili ana i ka mālama ola ma muli o kona ʻano hana ākea a me ka ʻike palekana maikaʻi. ʻAe kāna ʻano waha no ka mālama ʻana i kekahi mau maʻi ma waho o ka haukapila, e hāʻawi ana i nā mea maʻi me ka lāʻau lapaʻau kūpono e kūʻē i nā pathogens bacteria pilikia. Eia kekahi, hoʻohana ʻia ʻo linezolid i ka mālama ʻana i ka maʻi tuberculosis a me nā maʻi mycobacterial ʻē aʻe ma ke ʻano he ʻāpana o nā regimens therapy hui pū ʻia. ʻO kona ʻano hana kū hoʻokahi a me ka komo maikaʻi ʻana o nā ʻiʻo e lilo ia i mea hoʻohui waiwai i ka armamentarium no ka mālama ʻana i ka maʻi tuberculosis kūʻē i ka lāʻau a me nā maʻi mycobacterial nontuberculous. Ma nā wahi noiʻi, hoʻohana ʻia ʻo linezolid ma ke ʻano he kūlana kuhikuhi i ka hoʻāʻo ʻana i ka antimicrobial susceptibility e loiloi i ka ʻike o nā isolates bacterial i kēia antibiotic. Ma ka hoʻoholo ʻana i ka palena iki o ka inhibitory concentration (MIC) o ka linezolid e kūʻē i nā bacteria kikoʻī, hiki i nā mea noiʻi ke alakaʻi i nā hoʻolālā lapaʻau kūpono a nānā i nā ʻano kūʻē. Ma keʻano holoʻokoʻa, he kuleana koʻikoʻi ko linezolid i ka hoʻokele ʻana i nā maʻi bacteria Gram-positive paʻakikī, e hāʻawi ana i nā kauka i kahi koho lapaʻau ikaika a hilinaʻi hoʻi e kūʻē i nā pathogens pale lāʻau. ʻO kona pono i hoʻokumu maikaʻi ʻia, ka hoʻomanawanui, a me ka versatility e lilo ia i mea nui loa i ka hakakā ʻana i nā maʻi lele, ʻoi aku hoʻi nā mea i hoʻokumu ʻia e nā bacteria pale lāʻau.