N-Acetyl-D-Glucosamine CAS:7512-17-6 Mea Hana Mea Hoʻolako

N-ʻO Acetyl-D-Glucosamine ka N-acetyl derivative o ka glucosamine. Ma ke ʻano kemika, he amide ia ma waena o ka glucosamine a me ka waikawa acetic. ʻO kahi ʻāpana N-acetlyglucosamine hoʻokahi i hoʻopili ʻia i nā koena serine a i ʻole threonine ma nā protein nuklea a me nā cytoplasmic -O-GlcNAc, he hoʻololi protein post-translational ma nā wahi āpau. Pili nā protein i hoʻololi ʻia ʻo O-GlcNAc i ka ʻike ʻana i ke kūlana meaʻai o ke kaiapuni cellular a puni a me ka hoʻoponopono ʻana i ka hana o nā protein cellular e like me ia. Hoʻoponopono ʻo O-GlcNAc i nā pane cellular i nā hormones e like me ka insulin, hoʻomaka i kahi pane pale i ke kaumaha, hoʻololi i ka hiki o kahi cell ke ulu a māhelehele, a hoʻoponopono i ka transcription gene. I loko o ke kanaka, aia ia i loko o ka ʻili, ka cartilage a me ke kīʻaha koko ma ke ʻano he ʻāpana o ka hyaluronic acid, a me ka ʻiʻo iwi, cornea a me aorta ma ke ʻano he ʻāpana o keratan sulfate.