ʻO (S)-Ethyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride CAS:15912-56-8

(S) -ʻO ka Ethyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride ke kuleana koʻikoʻi ma ke ʻano he waena i ka synthesis o nā hui paʻakikī, bioactive me nā noi lāʻau lapaʻau hiki. ʻO kona hoʻokomo ʻia ʻana i loko o nā ʻōnaehana molekala e hiki ai i nā mea noiʻi ke ʻimi i nā moho lāʻau lapaʻau hou e kuhikuhi ana i nā wahi therapeutic e like me nā maʻi ʻōnaehana nerve waena, nā mea antipsychotic, a i ʻole nā ​​​​lāʻau analgesic. ʻO ke ʻano kū hoʻokahi o kēia hui e hoʻolauna i ka reactivity kikoʻī a me nā waiwai pharmacophoric, e lilo ia i mea waiwai no ka noiʻi kemika lāʻau lapaʻau. I nā hana ʻike lāʻau lapaʻau, hiki i kēia hui ke lawelawe ma ke ʻano he kumu hoʻomaka no ka hoʻolālā ʻana i nā moho lāʻau lapaʻau hiki, e hoʻohana ana i kona mau hiʻohiʻona kūkulu e hoʻololi i ka hana olaola a me nā waiwai pharmacokinetic. Eia kekahi, hiki i ke ʻano chiral o ka mole ke hoʻololi nui i kāna mau pilina me nā pahuhopu olaola, e hoʻopilikia paha i kona mau waiwai pharmacological a hoʻonui i kona pono i ka hoʻomohala ʻana i ka lāʻau. Eia kekahi, ma nā wahi hoʻonaʻauao a me nā ʻoihana, hiki i nā mea noiʻi ke hoʻohana i kēia poloka hale e hoʻomākaukau i nā hale waihona puke o nā derivatives like ʻole no nā haʻawina pilina hana-hana, e hoʻomaʻamaʻa ana i ka ʻike ʻana i nā hui alakaʻi me nā hopena olaola i makemake ʻia. ʻO kona kuleana i ka synthesis kemika e hoʻonui i ka hana ʻana o nā waena lāʻau lapaʻau a me ka hoʻomohala ʻana i nā ʻano hana synthetic hou, e hōʻike ana i kona pono ākea ma waena o nā aʻo ʻepekema. Ma keʻano holoʻokoʻa, he kuleana koʻikoʻi ko (S)-Ethyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride i ka ʻike ʻana i nā lāʻau lapaʻau hou a me ka noiʻi kemika, e hāʻawi ana i kahi kahua no ka hoʻomohala ʻana i nā molekala biologically active like ʻole a me nā mea lapaʻau waena.