Setmelanotide CAS:920014-72-8 Mea Hana Mea Hoʻolako

He agonist melanocortin-4 receptor (MC4R) ʻo Setmelanotide. ʻO kāna mau noi e pili ana i ka mālama ʻana i kekahi mau maʻi genetic e pili ana i ka momona, e like me ka hemahema o ka pro-opiomelanocortin (POMC), ka hemahema o ka leptin receptor (LEPR), a me ka maʻi Bardet-Biedl. Hoʻohana ʻia ʻo Setmelanotide e mālama i ka momona nui i nā poʻe maʻi me kēia mau kūlana genetic kikoʻī, ma ke kōkua ʻana i ka hoʻoponopono ʻana i ka makemake a me ke kaumaha o ke kino. ʻO nā hopena ʻaoʻao maʻamau e pili ana i nā hopena ma kahi injection, ka hyperpigmentation ʻili (nā ʻāpana ʻili i ʻoi aku ka ʻeleʻele ma mua o ka ʻili a puni), ka ʻeha poʻo a me nā hopena ʻaoʻao gastrointestinal (e like me ka nausea, ka maʻi diarrhea, a me ka ʻeha ʻōpū), a me nā mea ʻē aʻe. Ua hana ʻia nā kūkulu penile spontaneous i nā kāne a me nā hopena moekolohe maikaʻi ʻole i nā wahine me ka mālama ʻana. Ua hana pū ʻia ke kaumaha a me ka manaʻo pepehi kanaka me ka setmelanotide.