Simvastatin CAS:79902-63-9 Mea Hoʻolako Mea Hana

ʻO Simvastatin he semi-synthetic, ʻoi aku ka hydrophobic, analogue o lovastatin.E like me ka lovastatin, ʻo simvastatin kahi mea paʻa i ka HMG-CoA reductase a hoʻohana ʻia i ka lāʻau lapaʻau e hōʻemi i ka kolamu LDL.I kēia mau lā, ua lilo nā statins i mea noiʻi biochemical koʻikoʻi i ka biology cell.Hiki ke hoʻopili ʻia ko lākou komo ʻana i nā hanana he nui i kā lākou ʻano hana mua, akā naʻe, ʻaʻole i ʻike ʻia ke ʻano o ka hana o nā hopena ʻē aʻe. i ka mevalonate, kahi hana mua i ka biosynthesis cholesterol.Hoʻohana ʻia ia i ka mālama ʻana i ka hypercholesterolemia, ʻoiai e hoʻemi ana i nā pae o nā lipoproteins haʻahaʻa haʻahaʻa a me nā triglycerides, a hoʻonui i nā pae lipoprotein kiʻekiʻe.