Z-MeVal-OH CAS:42417-65-2

Hoʻohana nui ʻia kēia huahana e nā mea noiʻi a me nā ʻoihana lāʻau lapaʻau no ka hana ʻana o nā peptides e loaʻa ana nā koena N-methylvaline. Ua ʻike ʻia ʻo N-methylvaline no kona hiki ke hoʻonui i ke kūpaʻa conformational a me ka membrane permeability o nā peptides, e lilo ia i poloka hale waiwai nui i ka hoʻomohala ʻana i nā lāʻau lapaʻau a me nā therapeutics e pili ana i ka peptide. He maʻemaʻe loa ʻo Z-MeVal-OH a kūlike me nā reagents ʻē aʻe, e lilo ia i koho hilinaʻi no nā papahana synthesis peptide. He mea hana versatile ʻo Z-MeVal-OH no nā mea noiʻi ma nā kahua o ka biochemistry, pharmacology, a me ka ʻike ʻana i nā lāʻau lapaʻau. ʻO kona kūpaʻa, ka maʻemaʻe, a me ka hoʻohālikelike e lilo ia i mea nui i ka synthesis o nā peptides e loaʻa ana iā N-methylvaline, nona nā noi kūpono i ka hoʻomohala ʻana i nā lāʻau lapaʻau, ka noiʻi biological, a me nā hana therapeutic. Ma ka hoʻohui ʻana iā Z-MeVal-OH i loko o nā moʻo peptide, hiki i nā mea noiʻi ke hana i nā hui hou me ka bioactivity i hoʻomaikaʻi ʻia a me nā waiwai pharmacokinetic, e hoʻolaha ana i ke kahua o ka ʻike ʻana i nā lāʻau lapaʻau e pili ana i ka peptide.