2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium paʻakai he mea hoʻohui kemika i hoʻohana mau ʻia i nā hoʻokolohua diagnostic a me nā noiʻi.ʻO ia ka mea i hoʻopaʻa inoa ʻia o ka sialic acid, kahi ʻano mole mole kalapona i loaʻa ma ka ʻili o nā cell.
Hoʻohana ʻia kēia pūhui ma ke ʻano he substrate no nā enzymes i kapa ʻia ʻo neuraminidases, e hana ana e hoʻoneʻe i nā koena waikawa sialic mai nā glycoproteins a me glycolipids.Ke hana kēia mau enzymes i ka paʻakai sodium 2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid, hoʻokuʻu ia i kahi huahana fluorescent i kapa ʻia ʻo 4-methylumbelliferone.
Hiki ke ana a helu ʻia ka fluorescence i hana ʻia e ka pūhui, e hāʻawi ana i ka ʻike e pili ana i ka hana o nā enzymes neuraminidase.He mea maikaʻi loa kēia i ke aʻo ʻana i nā maʻi like ʻole a me nā kūlana e pili ana me ka aberrant sialic acid metabolism.
Hoʻohana ʻia ka pūhui no nā kumu diagnostic, e like me ka ʻike ʻana i nā maʻi viral e pili ana i ka hana neuraminidase.I loko o kēia mau ho'āʻo, hoʻohana ʻia ka pūhui e ʻike i ka hiki ʻana o nā maʻi viral kikoʻī a i ʻole ka loiloi i ka pono o nā neuraminidase inhibitors i nā lāʻau antiviral.