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Methylfolate (L-5 Methyl Calcium Tetrahydrofolate) CAS:134-35-0 Mea Hana Mea Hoʻolako
He metabolite folate ikaika ka 5-Methyltetrahydrofolic acid (5-MTHF). He kuleana koʻikoʻi kona i ka synthesis o ka methionine mai ka homocysteine ma o ka hāʻawi ʻana i ka hui methyl. ʻO ka 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) he isotope o ka huaora B9 kahi i pani ʻia ai nā kalapona glutamate ʻelima e ke kalapona 13C6.
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Creatine phosphate CAS:67-07-2 Mea Hana Mea Hoʻolako
ʻO Creatine phosphatehe waikawa phosphoamino i haku ʻia me ka creatine nona kahi hui phospho i hoʻopili ʻia ma ka naikokene mua o ka hui guanidino. He kuleana kona ma ke ʻano he metabolite kanaka a he metabolite ʻiole. He waikawa phosphoamino ia a he phosphagen. Pili ia i ka hana me kahi creatine. He waikawa conjugate ia o kahi N-phosphocreatinate (2-).
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ʻO ka Wikamina A Acid CAS:302-79-4 Mea Hana Mea Hoʻolako
ʻAkika Retinoic（ʻO Tretinoin）Hoʻohana pinepine ʻia i nā lāʻau lapaʻau dermatology, ʻo ia ka ʻoihana o ka huaora A (Victoria methanol) metabolic intermediates. Hoʻopilikia nui ia i ka ulu ʻana o nā iwi a me ka metabolism epithelial, hiki ke hoʻolaha i ka hoʻonui ʻana o nā cell epithelial a me nā hoʻonui hou ʻana, a hiki ke kāohi i ka hoʻonui ʻana a me ka hoʻokaʻawale ʻana o nā keratinocytes, no laila hiki ke hoʻi hou ka hyperkeratosis i ka maʻamau. No laila, he nui nā keratosis piha a piha ʻole paha, hyperkeratosis o nā maʻi i loaʻa kahi hopena therapeutic, mālama i nā ʻano maʻi ʻili like ʻole. Hiki i ka hoʻohana ʻana i ka lāʻau ke komo koke i ka ʻili topical, hiki ke hoʻonui nui i ka hoʻololi ʻana o nā cell epithelial. Loaʻa i kēia papa o nā lāʻau lapaʻau ka pale ikaika a wikiwiki i ka huna ʻana o nā kelepa sebaceous, hiki ke hōʻemi i ka huna sebum. Eia kekahi, loaʻa i ka huahana ka anti-tumor, paipai i ka ho'ōla ʻana i nā ʻeha a me nā hopena anti-inflammatory.
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L-Carnitine CAS:541-15-1 Mea Hana Mea Hoʻolako
L-Carnitine, i ʻike ʻia hoʻi ʻo L-carnitine a me ka huaora BT, ʻo ke ʻano kemika ʻo C7H15NO3, ʻo ka inoa kemika ʻo (R)-3-carboxyl-2-hydroxy-n, N, n-trimethylammonium propionate hydroxide paʻakai kūloko, a ʻo ka lāʻau lapaʻau ʻelele ʻo L-carnitine. He ʻano amino acid ia e paipai ana i ka hoʻololi ʻana o ka momona i ka ikehu.
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Chromium Polynicotinate CAS:64452-96-6 Mea Hana Mea Hoʻolako
He pauka ʻili maikaʻi ʻo Chromium Polynicotinate o ka hina uahi. He paʻa iki ka mea i ka mahana o ka lumi a ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai a me ka ethanol. ʻO ka hana o ka chromium he 3+. Hoʻohana nui ʻia i nā mea hoʻohui hānai, nā huahana olakino lapaʻau, nā mea hoʻohui meaʻai, a pēlā aku. ʻO kāna hana ka hoʻoulu ʻana i ka ulu ʻana o nā holoholona a me ka ulu ʻana, ka wikiwiki ʻana i ka hana ʻana, a me ka hoʻoulu ʻana i ka synthesis protein.
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N-Acetyl-D-Glucosamine CAS:7512-17-6 Mea Hana Mea Hoʻolako
N-ʻO Acetyl-D-Glucosamine ka N-acetyl derivative o ka glucosamine. Ma ke ʻano kemika, he amide ia ma waena o ka glucosamine a me ka waikawa acetic. ʻO kahi ʻāpana N-acetlyglucosamine hoʻokahi i hoʻopili ʻia i nā koena serine a i ʻole threonine ma nā protein nuklea a me nā cytoplasmic -O-GlcNAc, he hoʻololi protein post-translational ma nā wahi āpau. Pili nā protein i hoʻololi ʻia ʻo O-GlcNAc i ka ʻike ʻana i ke kūlana meaʻai o ke kaiapuni cellular a puni a me ka hoʻoponopono ʻana i ka hana o nā protein cellular e like me ia. Hoʻoponopono ʻo O-GlcNAc i nā pane cellular i nā hormones e like me ka insulin, hoʻomaka i kahi pane pale i ke kaumaha, hoʻololi i ka hiki o kahi cell ke ulu a māhelehele, a hoʻoponopono i ka transcription gene. I loko o ke kanaka, aia ia i loko o ka ʻili, ka cartilage a me ke kīʻaha koko ma ke ʻano he ʻāpana o ka hyaluronic acid, a me ka ʻiʻo iwi, cornea a me aorta ma ke ʻano he ʻāpana o keratan sulfate.
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Creatine Pyruvate CAS:55965-97-4 Mea Hana Mea Hoʻolako
ʻO Creatine Pyruvate kahi hui e komo pū ana me Creatine a me pyruvic acid a hoʻohana ʻia e nā mea kūkulu kino ma ke ʻano he mea hoʻohui e loaʻa ai nā hopena ergogenic a hoʻoheheʻe loa ʻia i ka wai. Ma kona ʻano hui, ʻoi aku ka hoʻoheheʻe ʻia o Creatine Pyruvate ma mua o ko lākou ʻano pākahi. Ua hōʻike ʻia nā haʻawina lapaʻau e hōʻemi ana ʻo Pyruvate i ka momona o ke kino me ka ʻole o ka hoʻopilikia ʻana i ka protein muscle, kahi ʻāpana koʻikoʻi i ka hoʻokō ʻana i ka nui o nā ʻiʻo lean. ʻO nā mea hoʻohui Creatine Pyruvate he kākoʻo meaʻai kūpono no nā mea pāʻani e ʻimi nei e hoʻonui i ka hana muscular a me ke ahonui i nā papahana hoʻoikaika kino kiʻekiʻe.
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ʻO ka Wikamina A Palmitat CAS:79-81-2 Mea Hana Mea Hoʻolako
No loko o kahi ʻano o nā hui i kapa ʻia ʻo retinoids ka Retinyl palmitate, he like kemika me ka huaora A. Hōʻike ia i kahi hopena maikaʻi i ka ʻike, ka ʻili a me ka hana pale, kāohi i ka hoʻonui ʻana o nā cell a pale i ka maʻi kanesa. He meaʻai koʻikoʻi ia a he hui therapeutic. ʻO All-trans-retinyl palmitate kahi ester all-trans-retinyl i loaʻa ma o ka condensation formal o ka hui carboxy o palmitic (hexadecanoic acid) me ka hui hydroxy o all-trans-retinol. Hoʻohana ʻia ia i nā huahana hoʻonaninani e mālama i nā maʻi ʻili like ʻole e like me ka acne, ka ʻelemakule ʻili, nā wrinkles, nā kiko ʻeleʻele, a pale pū i ka psoriasis. He kuleana kona ma ke ʻano he metabolite Escherichia coli, kahi metabolite xenobiotic kanaka a me kahi antioxidant. He retinyl palmitate a he ester all-trans-retinyl. Pili ia i ka hana me kahi all-trans-retinol.
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Benfotiamine CAS:22457-89-2 Mea Hana Mea Hoʻolako
ʻO S-Benzoylthiamine O-monophosphate (Benfotiamine) kahi amphiphilic S-acyl thiamine derivative. He huaora lipid-soluble ia. Loaʻa iā Benfotiamine kahi apo thiazole. ʻOi aku ka bioavailability o Benfotiamine ma mua o ka thiamine.
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Collagen Hydrolyzed CAS:92113-31-0 Mea Hana Mea Hoʻolako
Ua kapa ʻia hoʻi ka collagen hydrolyzed ʻo hydrolyzed collagen. ʻO ka hydrolyzed collagen kahi ʻano hou o ka huahana collagen, i hana ʻia mai ka collagen a i ʻole nā kumuwaiwai waiwai collagen. Ma waho aʻe o ka hoʻohuihui amino acid hiʻona o ka collagen (ma kahi o 30% o nā koena amino acid āpau he glycine), loaʻa iā ia he 15-30% o ʻelua mau waikawa amino i loaʻa pinepine ʻole i nā protein ʻē aʻe, proline a me 4-hydroxyproline. Ma waho aʻe o ka waikawa), loaʻa iā ia nā ʻano o ke kaumaha molekala liʻiliʻi, a ʻo ka hoʻohuihui ʻana he peptides liʻiliʻi me ke kaumaha molekala ma lalo o 3000.
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ʻO ka Vitamin E kūlohelohe CAS:59-02-9 Mea hana Mea hoʻolako
ʻO ka Vitamin E Aila kahi huaora momona-soluble, i ʻike ʻia hoʻi ʻo tocopherol. ʻO ia kekahi o nā antioxidants koʻikoʻi loa. He mau mea hoʻoheheʻe organik momona-soluble e like me ka ethanol, a ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai, wela, paʻa ka waikawa, base-labile. He ʻike ia i ka oxygen akā ʻaʻole ʻike i ka wela. A ʻoi aku ka haʻahaʻa o ka hana o ka huaora E i ka palai ʻana. Hoʻohui ʻia ka α-Tocopherol mai ka γ-tocopherol ma ka hana a ka enzyme γ-tocopherol methyltransferase. ʻO ia ke ʻano nui o ka Vitamin E i loko o ka plasma kanaka. Aia ia i loko o ka ʻaila hua pua nānālā.
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Curcumin (turmeric) 95% CAS:458-37-7 Mea Hana Mea Hoʻolako
ʻO Curcumin ka pigment melemele nui i loko o ka turmeric a me ka curry a he mau hana antioxidant, anti-inflammatory, a me antitumor. Hoʻopaʻa ia i ka hana nitric oxide (NO) (IC50 = 6 μM) a hoʻemi i ka hana inducible nitric oxide synthase (iNOS) i loko o nā pūnaewele RAW 264.7 i hoʻoulu ʻia e LPS. Hoʻopaʻa ʻo Curcumin i ka hoʻokuʻu ʻana o ka histamine a me nā cytokines inflammatory TNF-α, IL-1β, IL-6, a me IL-8 mai nā pūnaewele mast HMC-1. I loko o ke kino, hoʻemi ʻo curcumin i nā pae serum o ka histamine a me TNF-α, hoʻopaʻa i nā loli histopathological o ka mucosa nasal, a hoʻemi i ka helu o nā sneezing a me ka hamo ʻana i ka nasal i loko o kahi kumu hoʻohālike ʻiole o ka rhinitis i hoʻoulu ʻia e ovalbumin.
