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β-Nicotinamide Adenine Dinucleotide Phosphate Disodium Paʻakai CAS: 24292-60-2
β-Nicotinamide Adenine Dinucleotide Phosphate Disodium PaʻakaiHe coenzyme ia i hoʻolaha nui ʻia i loko o nā mea ola, komo i nā hopena oxidation-reduction. Hana ia ma ke ʻano he mea lawe electron i loko o kekahi mau hopena, e oxidized ʻokoʻa ʻia (NADP+) a hoʻemi ʻia (NADPH).β-Nicotinamide Adenine Dinucleotide Phosphate Disodium Paʻakaihe mea ia e hoʻopaʻa ʻia ai ka waikawa nicotinic amide adenine dinucleotide a me kahi molekole phosphate e ka pilina ester. He mea loaʻa hydrogen ia a hiki ke hoʻohana ʻia no ka hoʻomohala ʻana a me ka hoʻomohala ʻana i nā ʻano reagents diagnostic in vitro.
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β-Nicotinamide Adenine Dinucleotide Lithium paʻakai (NAD Lithium paʻakai) CAS:64417-72-7
β-Nicotinamide Adenine Dinucleotide Lithium paʻakaihe coenzyme kikowaena ia no ka metabolism. Loaʻa i loko o nā cell ola āpau, ua kapa ʻia ʻo NAD he dinucleotide no ka mea he ʻelua nucleotides i hui pū ʻia ma o kā lākou mau hui phosphate. Loaʻa i hoʻokahi nucleotide kahi adenine nucleobase a ʻo kekahi nicotinamide. Aia ʻo NAD i ʻelua ʻano: kahi ʻano oxidized a me ka hoʻemi ʻia, i hoʻopōkole ʻia ʻo NAD+ a me NADH (H no hydrogen), kēlā me kēia.
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Venlafaxine CAS:93413-69-5
He lāʻau antidepressant ʻo Venlafaxine o ka papa serotonin a me norepinephrine reuptake inhibitor (SNRI). Ua hoʻomohala mua ʻia kēia lāʻau e Wyeth ma 19Chemicalbook93 a ke kūʻai ʻia aku nei e Pfizer. Ua ʻae ʻia kēia lāʻau no ka mālama ʻana i ka maʻi kaumaha nui (MDD), ka maʻi hopohopo maʻamau (GAD), a me ke kaumaha e pili ana me ka hopohopo.
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ʻO Ciclopirox Ethanolamine CAS:41621-49-2 Mea Hana Mea Hoʻolako
He mea antifungal ākea ka Ciclopirox ethanolamine, hōʻike pū ia i ka hana antibacterial e kūʻē i nā bacteria Gram-positive a me Gram-negative he nui, a he mau waiwai anti-inflammatory. Hoʻohana ʻia ia i mea lapaʻau topical o ka ʻili fungal a me nā maʻi kui.
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Desvenlafaxine Succinate CAS:386750-22-7
ʻO Desvenlafaxine Succinate kahi mea hoʻopaʻa serotonin a me norepinephrine reuptake inhibitor (SNRI) i ʻāpono ʻia no ka mālama ʻana i ka maʻi kaumaha nui (MDD) ma ʻAmelika Hui Pū ʻIa i ka makahiki 2008. I mea e hoʻomaikaʻi ai i ka pono a me ka palekana o ka venlafaxine, ua ʻike a hoʻomohala ʻo Wyeth i kekahi o nā metabolites nui o ka venlafaxine, ʻo ia hoʻi ka O-desmethyl metabolite (desvenlafaxine).
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Doxazosin Mesylate CAS:77883-43-3 Mea Hana Mea Hoʻolako
ʻO Doxazosin mesylate kahi hui quinazoline he mea hoʻopaʻa koho o ka subtype alpha1 o nā mea loaʻa alpha adrenergic. ʻO Doxazosin mesylate kahi hanauna hou o ka quinazolone α1 receptor blocker i hoʻomohala ʻia e ka hui Pfizer (ʻAmelika Hui Pū ʻIa), He lōʻihi kona hapalua ola, e hoʻopuka ana i kona hopena o ka hoʻonui ʻana i nā kīʻaha koko, e hōʻemi ana i ke kū'ē ʻana o nā kīʻaha koko a me ka hoʻohaʻahaʻa ʻana i ke koko ma o ka pale ʻana i ka mea loaʻa a 1. Ua ʻōlelo ʻia ma waho ma ke ʻano he lāʻau lapaʻau laina mua no ka anti-hypertension a me ka mālama ʻana i ka maʻi prostate.
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L-Isoleucine CAS:73-32-5 Mea Hana Mea Hoʻolako
ʻO L-Isoleucine, i ʻike ʻia hoʻi ʻo Isoleucine, he waikawa amino ia he isomer o ka leucine. He mea nui ia i ka hana ʻana o ka hemoglobin a me ka hoʻoponopono ʻana i ke kō koko a me nā pae ikehu. ʻO L-Isoleucine kahi isomer o L-leucine a he waikawa amino koʻikoʻi. Hana ʻia ia mai ka threonine a he waikawa amino hydrophobic branched-chain.
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Captopril CAS:62571-86-2 Mea Hana Mea Hoʻolako
ʻO Captopril ka mea i aʻo nui ʻia o nā mea hoʻopaʻa enzyme hoʻololi angiotensin i manaʻo ʻia he lāʻau antihypertensive. Hoʻopaʻa ia i ka enzyme hoʻololi angiotensin, ka mea e kāohi ana i ka hoʻokumu ʻia ʻana o ka angiotensin II a hoʻomaha i kona hopena vasoconstricting ma nā kīʻaha arterial a me venous. Hoʻemi ʻia ke kaumaha peripheral vascular holoʻokoʻa, kahi e hopena ai i ka hoʻohaʻahaʻa ʻana o ke kaomi arterial.
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Candesartan CAS:139481-59-7 Mea Hana Mea Hoʻolako
He antagonist angiotensin II receptor I (AT1) ʻo Candesartan, IC50s=1.12 a me 2.86 nM no ka bovine adrenal cortex a me ka rabbit aorta. Hoʻopaʻa koho i ka ʻūlū ʻana o nā ʻāpana aortic rabbit i hoʻokomo ʻia e angiotensin II me ka ʻole o ka hopena i ka ʻūlū ʻana i hoʻokumu ʻia e nā mea ʻē aʻe e like me norepinephrine, KCl, serotonin, PGF2α a i ʻole endothelin.
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ʻO Candesartana Cilexetila CAS:145040-37-5
ʻO Candesartan Celexetil kahi analog ester o ka angiotensin II antagonist Candesartan (sc-217825). ʻO ka antagonism o kēia receptor e pale aku i ka hoʻopaʻa ʻana o ka angiotensin II, kahi vasoconstrictor ikaika. Loaʻa i kēia ka hopena holoʻokoʻa o ka vasodilation a me ka hoʻonui ʻia o ka nui o ke koko capillary. ʻO Candesartan Celexetil Ester kahi mea hoʻopaʻa o AT1.
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Bupropion CAS:34911-55-2 Mea Hana Mea Hoʻolako
He ketone ʻala ka Bupropion ʻo ia hoʻi ka propiophenone e lawe ana i kahi hui tert-butylamino ma ke kūlana 2 a me kahi pani chloro ma ke kūlana 3 ma ke apo phenyl. Loaʻa iā ia kahi kuleana ma ke ʻano he antidepressant, kahi mea haumia kaiapuni a me kahi xenobiotic. He hui amino lua ia, he lālā o nā monochlorobenzenes a me kahi ketone ʻala.
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ʻO Bezafibrate CAS:41859-67-0 Mea Hana Mea Hoʻolako
ʻO Bezafibrate kahi amide waikawa monocarboxylic i loaʻa ma o ka hoʻohuihui maʻamau o ka hui carboxy o ka waikawa 4-chlorobenzoic me ka hui amino o ka waikawa 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic. Hoʻohana ʻia ʻo Benafibrate no ka mālama ʻana i ka hyperlipidaemia. Loaʻa iā ia kahi kuleana ma ke ʻano he xenobiotic, kahi mea haumia kaiapuni, kahi geroprotector a me kahi lāʻau antilipemic. He waikawa monocarboxylic ia, kahi ether ʻala, he lālā o nā monochlorobenzenes a me kahi amide waikawa monocarboxylic. Pili ia i ka hana me ka waikawa propionic.
