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Amylase, a-, Aspergillus oryzae CAS:9001-19-8 Kumukūʻai Mea Hana
AmHe enzyme ka ylase e kōkua i ka wāwahi ʻana o ka starch i nā kō maʻalahi e like me ka maltose a me ka glucose. Hana pinepine ʻia ia e nā meaola like ʻole, me nā bacteria, fungi, a me nā mea kanu.
ʻO ka "a-" i loko o ka "a-amylase" e pili ana i ke ʻano o ka amylase e hydrolyzes pono i nā pilina alpha-1,4 glycosidic kūloko i loko o ka molekole starch. ʻO ka hopena kēia i ka hana ʻana o nā polysaccharides kaulahao pōkole, hiki ke wāwahi hou ʻia i glucose e nā enzymes amylase ʻē aʻe.
ʻO Aspergillus oryzae kahi ʻano fungi filamentous i ʻike ʻia no kona hiki ke hana i ka nui o ka amylase. Hoʻohana nui ʻia ia i nā kaʻina hana enzyme ʻoihana ma muli o kāna hana amylolytic ikaika. Hoʻohana nui ʻia nā enzymes i hana ʻia e Aspergillus oryzae, me ka a-amylase, i nā ʻoihana like ʻole, e like me ka meaʻai, ka hana pia, ka lole, a me ka hana detergent.
I ka ʻoihana meaʻai, hoʻohana pinepine ʻia ka a-amylase i loaʻa mai Aspergillus oryzae i ka hoʻomoʻa ʻana, ka hana ʻana i ka pia, a me ka hana ʻana i ka starch. Kōkua ia i ka wāwahi ʻana i ka starch i loko o ka palaoa, ka malt, a me nā mea maka ʻē aʻe, e hoʻomaʻalahi ana i ka hoʻololi ʻana o nā kalapona paʻakikī i nā kō maʻalahi hiki ke hoʻololi ʻia e ka hū a i ʻole ka bacteria i ka wā fermentation. Hoʻohana ʻia kēia enzyme i ka hana lole e hoʻomaʻalahi i ka wehe ʻana i nā mea hoʻonui i hoʻokumu ʻia i ka starch mai nā lole.
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Aprotinin CAS:9087-70-1 Kumukūʻai Mea Hana
He mea hoʻopaʻa kūlohelohe ʻo Aprotinin i nā ʻano enzyme proteolytic like ʻole, me ka trypsin, chymotrypsin, a me ka plasmin. Hoʻohana pinepine ʻia ia i nā wahi lapaʻau, ʻoi aku hoʻi i nā ʻokiʻoki cardiovascular, e hōʻemi i ke kahe koko a hoʻemi i ke kahe koko. Hana ʻo Aprotinin ma ka pale ʻana i ka hana o kēia mau enzymes, ka mea e pili ana i ka haki ʻana o nā clots koko a me ka hōʻino ʻana o ka fibrin, kahi protein e kōkua ai i ka hoʻokumu ʻana o ka clot. Ma ka pale ʻana i ka hana enzymatic nui, kōkua ʻo aprotinin i ka mālama ʻana i ke kūpaʻa o nā clots koko, no laila e hōʻemi ana i nā pilikia kahe koko i ka wā o ke ʻoki ʻana.
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Thrombin CAS:9002-04-4 Kumukūʻai Mea Hana
ʻO Thrombin kahi enzyme koʻikoʻi e pili ana i ke kāpili ʻana o ke koko, i ʻike ʻia hoʻi ʻo ke kāpili ʻana. Hana ʻia ia mai kona protein mua, ʻo prothrombin, i ka pane ʻana i ka ʻeha a i ʻole ka hōʻino ʻana i nā kīʻaha koko. He kuleana koʻikoʻi ko Thrombin i ka hoʻokumu ʻana o kahi ʻūpā koko, kahi e kōkua ai i ka pale ʻana i ke kahe nui ʻana o ke koko a hoʻolaha i ka ho'ōla ʻana o nā ʻeha.
Ke hoʻāla ʻia, hoʻololi ʻo thrombin i ka fibrinogen, kahi protein ʻē aʻe i loko o ke koko, i fibrin. Hoʻokumu ʻo Fibrin i kahi ʻano mesh-like e hoʻopaʻa ana i nā platelets a me nā ʻulaʻula koko, e hana ana i kahi clot koko paʻa. Hoʻāla pū ʻo Thrombin i nā mea coagulation ʻē aʻe, e hoʻonui ana i ke kaʻina hana clotting.
Ma waho aʻe o kona kuleana i ke kūkulu ʻana i nā clot, he mau hana koʻikoʻi ko ka thrombin. Hoʻoulu ia i ka ho'ōla ʻana o nā ʻeha ma ka hoʻoulu ʻana i ka neʻe ʻana a me ka ulu ʻana o nā cell e pili ana i ka hoʻoponopono ʻana i nā ʻiʻo. Hana pū ʻo Thrombin ma ke ʻano he vasoconstrictor, e hoʻohaiki ana i nā kīʻaha koko a hōʻemi i ke kahe koko i kahi i hōʻeha ʻia.
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Urease CAS:9002-13-5 Kumukūʻai Mea Hana
ʻO Urease kahi enzyme e hoʻololi i ka hydrolysis o ka urea i loko o ka ammonia a me ke kalapona dioxide. Hana ʻia ia e nā microorganisms like ʻole, me nā bacteria, fungi, a me nā mea kanu. He mea nui ka Urease no ka metabolism nitrogen a he kuleana koʻikoʻi kāna i nā kaʻina hana olaola like ʻole, e like me ka hydrolysis urea i loko o nā puʻupaʻa a me ka hoʻohui ʻana o ka nitrogen i nā mea kanu. Loaʻa iā ia nā noi ʻoihana, me ka ʻike ʻana i nā bacteria hana urease, nā mea hoʻouluulu urea, a me ka ʻike ʻana i nā mea hoʻopaʻa urease no ka mālama ʻana i kekahi mau maʻi.
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ʻO ka Leupeptin hemisulfate CAS: 103476-89-7
ʻO Leupeptin hemisulfate kahi mea hoʻopale protease i hoʻohana nui ʻia i ka noiʻi biochemical a me biomedical. Loaʻa ia mai nā bacteria Streptomyces a hana ma ke kāohi ʻana i ka hana o nā proteases like ʻole, me ka trypsin, chymotrypsin, a me ka plasmin.
Hoʻohana pinepine ʻia ʻo Leupeptin hemisulfate i nā hoʻokolohua hale hana e pale aku i ka hōʻino ʻana o ka protein i makemake ʻole ʻia, no ka mea hiki i nā protease ke hōʻino i nā protein a me nā peptides, e hoʻopilikia ana i nā hopena hoʻokolohua. Ma ka pale ʻana i ka hana protease, kōkua ʻo leupeptin hemisulfate i ka hoʻopaʻa ʻana i nā protein a mālama i ko lākou kūpaʻa i ka wā o nā hoʻokolohua.
Eia kekahi, ua hoʻohana ʻia ka leupeptin hemisulfate i nā haʻawina moʻomeheu cell e noiʻi i nā kuleana o nā proteases i nā kaʻina hana cellular like ʻole, e like me ka hōʻailona cell, apoptosis, a me ka protein turnover.
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Lipase mai ka pancreas puaʻa CAS:9001-62-1
ʻO Lipase kahi enzyme e hoʻoulu ai i ka hydrolysis o nā lipids, ʻo ia hoʻi ka wāwahi ʻana o nā triglycerides i nā waikawa momona a me ka glycerol. Hana ʻia ia e nā meaola like ʻole, me nā holoholona, nā mea kanu, a me nā microorganism. He kuleana koʻikoʻi ko Lipase i ka ʻai ʻana, no ka mea, kōkua ia i ka wāwahi ʻana a me ka omo ʻana o nā momona meaʻai i loko o ka ʻōpū liʻiliʻi. Eia kekahi, he nui nā noi o lipase i nā ʻoihana e like me ka hana ʻana i ka meaʻai, ka hana ʻana i nā mea holoi, nā lāʻau lapaʻau, a me ka hana biofuel. ʻO kona hiki ke hydrolyze i nā lipids e lilo ia i mea waiwai no nā hana e like me ka hoʻololi ʻana o ka lipid, ka hoʻonui ʻana i ka ʻono, a me ka unuhi ʻana i ka aila.
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Lysostaphin CAS:9011-93-2 Kumukūʻai Mea Hana
He enzyme antimicrobial ikaika ʻo Lysostaphin e kuhikuhi pono ana a pepehi iā Staphylococcus aureus, kahi bacteria kuleana no nā maʻi like ʻole i loko o kānaka. Loaʻa ia mai ka bacteria Staphylococcus simulans a loaʻa iā ia ka hiki ke wāwahi i ka paia cell o S. aureus, e alakaʻi ana i kona luku ʻia.
Hoʻopili pono ka enzyme i ka papa peptidoglycan o ka paia cell bacteria, e hoʻopilikia ana i kona ʻano a hoʻoulu i ka lysis bacteria. ʻO kēia ʻano hana kūikawā e hoʻolilo i ka lysostaphin i mea kūpono loa e kūʻē i nā ʻano S. aureus, me nā mea i kūʻē i nā antibiotics i hoʻohana pinepine ʻia.
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ʻO ka L-Lactate dehydrogenase CAS:9001-60-9
ʻO ka L-Lactate dehydrogenase (LDH) kahi enzyme e pāʻani ana i kahi kuleana koʻikoʻi i ka metabolism ikehu cellular, ʻoi aku hoʻi i ka hoʻololi ʻana o ka pyruvate i ka lactate. Hoʻoulu ia i ka hoʻololi hoʻohuli ʻia o L-lactate i pyruvate, me ka hoʻohana ʻana iā NAD+ ma ke ʻano he cofactor.
Loaʻa ka LDH i nā ʻiʻo like ʻole o ke kino, me ke akepaʻa, ka puʻuwai, nā ʻiʻo, a me nā hunaola koko ʻulaʻula. Hiki i kona pae hana ke lawelawe ma ke ʻano he hōʻailona diagnostic no kekahi mau maʻi, e like me ka hōʻino ʻana o ke akepaʻa, ka myocardial infarction, a me kekahi mau ʻano maʻi kanesa.
ʻO ka hana nui o LDH ka mālama ʻana i ke kaulike o ka ikehu o ke kelepona ma o ka hoʻomaʻamaʻa ʻana i ka hoʻololi ʻana o ka pyruvate, kahi huahana o ka glycolysis, i lactate. Hana ʻia kēia kaʻina hana, i ʻike ʻia ʻo ka anaerobic glycolysis, i ka wā ʻaʻohe o ka oxygen a hiki i nā kelepona ke hoʻomau i ka hana ʻana i ka ikehu ke kaupalena ʻia ka lako o ka oxygen.
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Pepsin CAS:9001-76-7 Kumukūʻai Mea Hana
He enzyme digestive ka Pepsin i loaʻa i loko o ka ʻōpū e pāʻani ana i kahi kuleana koʻikoʻi i ka ʻeli ʻana a me ka uhaki ʻana o nā protein. No kahi hui o nā enzymes i kapa ʻia ʻo protease, nona ke kuleana no ka uhaki ʻana i nā protein i nā peptides liʻiliʻi a me nā waikawa amino, e ʻae ana i ko lākou omo ʻana i loko o ka ʻōpū liʻiliʻi.
Hoʻopuka ʻia a hoʻokuʻu ʻia ʻo Pepsin e nā pūnaewele e uhi ana i ka ʻōpū, i ʻike ʻia ʻo nā cell chief, ma ke ʻano hana ʻole i kapa ʻia ʻo pepsinogen. Ke komo ka meaʻai i loko o ka ʻōpū, hoʻoulu ia i ka hoʻokuʻu ʻana o ka waikawa gastric, ka mea e hoʻololi i ka pepsinogen i kona ʻano hana, pepsin. Hana maikaʻi ʻo Pepsin i kahi ʻano acidic, ʻoiai ʻo ka pH haʻahaʻa o ka ʻōpū e kōkua i ka hoʻoulu a mālama i kāna hana enzymatic.
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ʻO ka mea hoʻohui protein kinase KT5823 CAS:126643-37-6
ʻO ka protein kinase supplement KT5823 kahi mea hoʻopaʻa mole liʻiliʻi e kuhikuhi pono ana a kāohi i ka hana protein kinase. ʻO nā protein kinases nā enzymes e phosphorylate i nā protein ma ka hoʻohui ʻana i nā hui phosphate i nā koena amino acid kikoʻī, ʻo ia hoʻi ka serine, threonine, a i ʻole tyrosine. He kuleana koʻikoʻi kēia kaʻina hana phosphorylation i nā ala hōʻailona cellular like ʻole, e hoʻoponopono ana i ka hana protein, a me ke kāohi ʻana i nā kaʻina hana cellular e like me ka ulu ʻana o ke cell, ka mahele ʻana, ka hoʻokaʻawale ʻana, a me ka apoptosis.
Hoʻohana pinepine ʻia ʻo KT5823 i nā haʻawina noiʻi e noiʻi i ka hana a me nā ala hōʻailona o nā protein kinases. Ma ka pale ʻana i nā protein kinases, hiki iā KT5823 ke kōkua i nā mea noiʻi e hoʻoholo i nā protein a me nā ala kikoʻī i hoʻopilikia ʻia e ka hana kinase. Hiki i kēia ʻike ke lilo i mea ʻike i ka hoʻomaopopo ʻana i ke kuleana o nā protein kinases i nā hana cellular a me ka ʻike ʻana i nā pahuhopu therapeutic hou.
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ʻO Pyridoxal-5′-phosphate monohydrate CAS:41468-25-1
ʻO Pyridoxal-5′-phosphate monohydrate, i ʻike ʻia hoʻi ʻo PLP, ke ʻano hana o ka huaora B6. He coenzyme koʻikoʻi ia e pili ana i nā ʻano hana enzymatic like ʻole i loko o ke kino. He kuleana koʻikoʻi ko PLP i ka metabolism amino acid, ka synthesis neurotransmitter, a me ka synthesis o heme, kahi ʻāpana o ka hemoglobin.
Hana ʻo PLP ma ke ʻano he coenzyme ma o ka hoʻopaʻa ʻana i nā enzymes kikoʻī a me ke kōkua ʻana i nā hopena kemika. Hana ia ma ke ʻano he mea hoʻoulu, e kōkua ana i ka hoʻololi ʻana o nā mea like ʻole, e like me nā waikawa amino, i nā huahana like ʻole. He mea nui loa ka PLP i ka metabolism o nā waikawa amino, e like me ka hoʻololi ʻana o ka tryptophan i serotonin, a i ʻole ka haki ʻana o ka glycine i serine.
Ma waho aʻe o kāna kuleana i ka metabolism amino acid, pili pū ka PLP i ka synthesis o nā neurotransmitters e like me dopamine, norepinephrine, a me ka gamma-aminobutyric acid (GABA). He mea nui kēia mau neurotransmitters no ka hana kūpono o ka lolo a pili i ka hoʻoponopono ʻana i ke ʻano, ka ʻike, a me ka hoʻoili ʻana o nā hōʻailona ma waena o nā cell nerve.
Eia kekahi, pono ka PLP no ka hana ʻana o ka heme, kahi ʻāpana o ka hemoglobin i loaʻa i loko o nā hunaola koko ʻulaʻula. ʻO ka Hemoglobin ke kuleana no ka lawe ʻana i ka oxygen ma ke kino holoʻokoʻa, e hana ana i ka PLP he mea nui no ka mālama ʻana i nā pae oxygen maʻamau a me ka hōʻoia ʻana i ka hana pono o nā ʻano kino a me nā ʻiʻo like ʻole.
Ma muli o kona koʻikoʻi i nā kaʻina hana biochemical he nui, ua ʻōlelo ʻia ka hoʻopihapiha PLP i kekahi manawa no nā poʻe me kekahi mau kūlana olakino a i ʻole nā hemahema e hoʻopilikia ai i ka metabolism vitamin B6. Loaʻa ia ma ke ʻano hoʻopihapiha a hiki ke kuhikuhi ʻia e nā mea lawelawe olakino no nā pono kikoʻī.
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ʻO ka Reductase, glutathione CAS:9001-48-3
ʻO Glutathione reductase kahi enzyme e pāʻani ana i kahi kuleana koʻikoʻi i ka mālama ʻana i ke kaulike o ka glutathione i hoʻemi ʻia a me ka oxidized (GSH/GSSG) i loko o nā cell. ʻO Glutathione kahi tripeptide i haku ʻia me nā waikawa amino glycine, cysteine, a me glutamate. Hana ia ma ke ʻano he antioxidant cellular nui a pili i nā kaʻina hana cellular like ʻole, me ka detoxification, synthesis DNA a me ka hoʻoponopono ʻana, a me ka synthesis protein.
Hoʻoikaika ka Glutathione reductase i ka hōʻemi ʻana o ka glutathione oxidized (GSSG) i kona ʻano i hoʻemi ʻia (GSH) ma o ka hoʻohana ʻana iā NADPH (nicotinamide adenine dinucleotide phosphate) ma ke ʻano he cofactor. He mea nui kēia hopena no ka mālama ʻana i ke kūlana i hoʻemi ʻia o ka glutathione i loko o nā cell, no ka mea hiki i ka GSSG ke hōʻiliʻili i ke alo o ke kaumaha oxidative.
Ma ka mālama ʻana i ka lakio kūpono o GSH i GSSG, kōkua ka glutathione reductase i ka pale ʻana i nā cell mai ka pōʻino oxidative i hoʻokumu ʻia e nā reactive oxygen species (ROS) a me nā molekala ʻino ʻē aʻe. Hana ia ma ke ʻano he mea nui i ka ʻōnaehana pale antioxidant o nā cell.
Eia kekahi, pili pū ka glutathione reductase i ka hana hou ʻana i ka glutathione disulfide (GSSG) i hana ʻia i ka wā o nā kaʻina hana metabolic like ʻole, e hōʻoia ana i ka loaʻa ʻana o ka glutathione i hoʻemi ʻia (GSH) no kāna mau hana cellular he nui.
