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Beta-Amylase CAS:9000-91-3 Kumukūʻai Mea Hana
ʻO Beta-amylase kahi enzyme e pāʻani ana i kahi hana koʻikoʻi i ka metabolism carbohydrate, ʻoi aku hoʻi i ka haki ʻana a i ʻole ka hydrolysis o nā molekala starch. Hoʻoulu ia i ka ʻoki ʻana o nā pilina α-1,4-glycosidic i loko o ka starch, e hoʻokuʻu ana i ka maltose a me kahi ʻāpana liʻiliʻi i kapa ʻia he palena dextrin.
Hana ʻia kēia enzyme i loko o nā meaola like ʻole, e like me nā mea kanu, nā bacteria, a me nā fungi, a hoʻohana nui ʻia i nā ʻoihana e like me ka hana pia, ka hoʻomoʻa ʻana, a me ka hana biofuel.
I ka hana ʻana i ka pia, he kuleana koʻikoʻi ko ka beta-amylase i ka hoʻololi ʻana o nā starches i loko o nā hua malted i nā kō fermentable i ka wā o ke kaʻina hana kuʻi, e kōkua ana i ka hana ʻana o ka waiʻona e ka hū. I ka hoʻomoʻa ʻana, kōkua ia i ka wāwahi ʻana i nā starches i nā kō, e kōkua ana i ka browning a me ka hoʻomohala ʻana o ka ʻono o nā mea i hoʻomoʻa ʻia. I ka hana biofuel, hoʻohana ʻia ka beta-amylase i ka hydrolysis o ka biomass i hoʻokumu ʻia i ka starch e loaʻa ai nā kō fermentable i hoʻohana ʻia no ka hana ʻana i ka ethanol.
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ʻO ka bromelain mai ke kumu paina CAS: 37189-34-7
He hui ʻana o nā enzymes ka Bromelain i loaʻa mai ke kumu o ka mea kanu paina (Ananas comosus). Hana nui ʻia ia me nā proteases, ʻo ia hoʻi nā enzymes e wāwahi i nā protein. Ua hoʻohana ʻia ʻo Bromelain no nā kenekulia i ka lāʻau lapaʻau kuʻuna ma ke ʻano he lāʻau lapaʻau kūlohelohe no nā ʻano maʻi like ʻole.
Ma muli o kona mau waiwai hoʻoheheʻe protein, hoʻohana pinepine ʻia ka bromelain ma ke ʻano he mea kōkua i ka hoʻoheheʻe ʻana, e kōkua ana i ka hoʻomaikaʻi ʻana i ka haki ʻana a me ka omo ʻana o nā protein i loko o ka ʻōnaehana hoʻoheheʻe. Ua aʻo ʻia hoʻi no kona mau hopena anti-inflammatory a me nā pono kūpono no ka hōʻemi ʻana i ka pehu, ka ʻeha, a me ka ʻeha.
Ma waho aʻe o kona mau waiwai digestive a me nā anti-inflammatory, ua noiʻi ʻia ka bromelain no kona hiki i nā ʻano hana therapeutic ʻē aʻe, me ka ho'ōla ʻana i nā ʻeha, ke kākoʻo ʻana i ka ʻōnaehana pale, a me ke olakino hanu.
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Mea Hoʻopaʻa Calpain IV CAS:133407-82-6
ʻO Calpain Inhibitor IV kahi ʻano lāʻau lapaʻau e kuhikuhi pono ana a kāohi i ka hana o ka enzyme calpain. ʻO Calpain kahi enzyme protease e hilinaʻi ana i ka calcium e pāʻani ana i kahi hana i nā kaʻina hana cellular like ʻole, me ka hōʻailona cell, apoptosis, a me ka hoʻoponopono hou ʻana o cytoskeletal.
Ma ke kāohi ʻana i ka calpain, kōkua ʻo Calpain Inhibitor IV i ka pale ʻana i ka hoʻoulu nui ʻana a me ka hoʻomalu ʻole ʻia o kēia enzyme, hiki ke alakaʻi i ka hōʻino ʻana o nā cellular a me ka hana pono ʻole. Hiki i kēia kāohi ke lilo i mea maikaʻi i nā kūlana kahi i pili ai ka overactivity calpain, e like me nā maʻi neurodegenerative e like me nā maʻi Alzheimer a me Parkinson, ka ʻeha ischemic, a i ʻole nā kūlana degeneration muscle.
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ʻO Carboxypeptidase B CAS:9025-24-5
ʻO Carboxypeptidase B kahi enzyme e pāʻani ana i kahi kuleana koʻikoʻi i ka hoʻoheheʻe ʻana o ka protein a me ka metabolism. ʻO ke kikoʻī, hoʻoulu ia i ka hydrolysis o nā pilina peptide ma ka hopena C-terminal o nā protein, e hopena ana i ka wehe ʻana o nā waikawa amino pākahi.
He kikoʻī loa ʻo Carboxypeptidase B no nā waikawa amino kumu, e like me ka lysine a me ka arginine, a he kūpono loa ia i ka ʻoki ʻana i kēia mau koena. Loaʻa pinepine ia i loko o nā mea huna pancreatic a pili i ke kahua hope o ka hoʻoheheʻe ʻana o ka protein i loko o ka ʻōpū liʻiliʻi.
Hoʻohana ʻia kēia enzyme i nā noi hoʻokolohua like ʻole, me ke kaʻina hana protein, ka peptide synthesis, a me ka nānā ʻana i ka protein. ʻO ka hiki o ka carboxypeptidase B ke ʻoki pono i nā waikawa amino C-terminal o nā protein e lilo ia i mea hana waiwai nui no ke aʻo ʻana i ke ʻano a me ka hana o ka protein.
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Carboxypeptidase,dipeptidyl, A CAS:9015-82-1
ʻO Carboxypeptidase kahi enzyme e hoʻoulu ai i ka hydrolysis (ka haki ʻana) o nā pilina peptide ma ka hopena carboxyl (C-terminal) o nā peptides a me nā protein. Kōkua ia i ka ʻeli ʻana a me ka hana ʻana o nā protein ma ka ʻoki ʻana i nā waikawa amino pākahi mai ka hopena o kahi kaulahao peptide. Ua hoʻokaʻawale ʻia nā Carboxypeptidases i ʻelua ʻano: exopeptidases, kahi e wehe ai i nā waikawa amino hoʻokahi i ka manawa mai ka hopena C-terminal, a me endopeptidases, kahi e ʻoki ai i nā pilina peptide i loko o ke kaulahao peptide. He kuleana koʻikoʻi kēia mau enzymes i nā kaʻina hana olaola like ʻole, me ka metabolism protein, ka hoʻoponopono ʻana o nā hormones, a me ka hoʻoponopono ʻana i ka hana enzymatic.
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Coenzyme A sodium salt hydrate CAS:55672-92-9
ʻO Coenzyme A sodium salt hydrate kahi ʻano wai-hoʻoheheʻe ʻia o Coenzyme A (CoA), kahi coenzyme koʻikoʻi e pili ana i nā ala metabolic like ʻole. He kuleana koʻikoʻi kona i ka wāwahi ʻana i nā momona, nā kalapona, a me nā protein, a me ka synthesis o nā molekala koʻikoʻi e like me nā waikawa momona a me ka cholesterol. Hoʻohana pinepine ʻia ka Coenzyme A sodium salt hydrate i ka noiʻi biochemical a me nā lāʻau lapaʻau ma ke ʻano he mea hoʻohui e aʻo ai i ka metabolism cellular a me nā kaʻina hana e pili ana.
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5-Nitro-1,10-phenanthroline CAS:4199-88-6
He hui kemika ʻo 5-Nitro-1,10-phenanthroline me ke ʻano molekala C12H6N4O2. No ka ʻohana o nā phenanthroline derivatives a loaʻa iā ia kahi hui nitro (-NO2) i hoʻopili ʻia i ke kūlana 5 o ka ʻōnaehana apo phenanthroline.
Ua ʻike ʻia kēia hui no kona hiki ke hana i nā hui paʻa me nā ion metala, ʻoiai nā ion metala hoʻololi. Hoʻonui ka hui nitro i kona mau waiwai complexation a hoʻolilo iā ia i mea pono i nā noi like ʻole e like me ke kemika analytical, catalysis, a me ke kemika hoʻohui.
Ua hoʻohana ʻia ʻo 5-Nitro-1,10-phenanthroline ma ke ʻano he chelator, ʻo ia hoʻi ke hana nei i nā pilina paʻa me nā ion metala ma ka hāʻawi ʻana i nā hui lone o nā electrons. ʻAe kēia i ka kaohi pololei a me ka hoʻoponopono ʻana i nā wahi hoʻonohonoho metal-ion.
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ʻO ka paʻakai sodium Acetyl coenzyme A CAS: 102029-73-2
ʻO ka paʻakai sodium Acetyl coenzyme A (acetyl-CoA) kahi mea i hana ʻia o ka acetyl-CoA. Hoʻohana pinepine ʻia ia i ka noiʻi hale hana a me nā haʻawina biochemical.
ʻO ka hoʻohana nui ʻana o ka paʻakai sodium acetyl-CoA i nā haʻawina metabolism cellular, ʻoi aku hoʻi i ka noiʻi ʻana i ke kuleana o acetyl-CoA i nā ala metabolic like ʻole. Hana ʻo Acetyl-CoA ma ke ʻano he precursor no ka synthesis o nā waikawa momona, cholesterol, a me nā kino ketone, a me ka pāʻani ʻana i kahi kuleana koʻikoʻi i ka hana ikehu ma o ke kaʻina hana waikawa citric (i ʻike ʻia hoʻi ʻo ke kaʻina hana Krebs).
Eia kekahi, pili ka acetyl-CoA i ka acetylation o nā protein, DNA, a me nā histones, hiki ke hoʻopilikia i ka hōʻike ʻana o nā gene a me ka hoʻoponopono hou ʻana o chromatin. No laila, hiki ke hoʻohana ʻia ka paʻakai sodium acetyl-CoA i nā haʻawina e kālele ana i kēia mau hoʻololi epigenetic a me ko lākou hopena i ka hana o ke kelepona.
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Puromycin dihydrochloride CAS:58-58-2 Kumukūʻai Mea Hana
He lāʻau antibiotic ikaika ka Puromycin dihydrochloride i hoʻohana pinepine ʻia i ka biology molecular a me ka noiʻi biology cell. Hoʻopaʻa ia i ka synthesis protein ma o ka hoʻopau mua ʻana i ka synthesis protein i ka wā unuhi. He kūpono ka Puromycin e kūʻē i nā cell prokaryotic a me eukaryotic a he mea pono loa ia no ke koho ʻana a me ka hoʻokaʻawale ʻana i nā cell i hoʻololi ʻia i ka genetic a i ʻole transfected me kahi gene kūʻē puromycin. Hoʻohana pinepine ʻia ia i nā hoʻonohonoho hale hana e aʻo i ka hōʻike ʻana o ka gene, ka synthesis protein, a e hana i nā laina cell paʻa me nā hoʻololi genetic kikoʻī.
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ʻAcetylcholinesterase CAS:9000-81-1
ʻO nā Anticholinesterases kahi papa o nā lāʻau lapaʻau a i ʻole nā kemika e kāohi ana i ka hana o ka enzyme acetylcholinesterase. ʻO Acetylcholinesterase ke kuleana no ka wāwahi ʻana i ka neurotransmitter acetylcholine i loko o ke kino. Ma ka pale ʻana i kēia enzyme, hoʻonui nā anticholinesterases i nā pae o ka acetylcholine, e alakaʻi ana i ka hoʻonui ʻia o ka hana cholinergic i loko o nā ʻōnaehana nerve waena a me peripheral.
ʻO ka hoʻohana nui ʻana o nā anticholinesterases i ka mālama ʻana i nā maʻi neurological e like me ka maʻi Alzheimer a me ka myasthenia gravis. I ka maʻi Alzheimer, manaʻo kēia mau lāʻau lapaʻau e hoʻoikaika i ka neurotransmission cholinergic a hiki ke hoʻolohi i ka emi ʻana o ka noʻonoʻo. I ka myasthenia gravis, kōkua nā anticholinesterases i ka hoʻomaikaʻi ʻana i ka hoʻoili neuromuscular a me ka ikaika o nā ʻiʻo.
ʻO nā hoʻohana ʻē aʻe o nā anticholinesterases e pili ana i ka ʻike a me ka mālama ʻana i ka lāʻau make anticholinergic, ʻoi aku hoʻi mai kekahi mau insecticides a i ʻole nā mea aʻalolo. Hiki i kēia mau mea ke hoʻoulu nui i nā mea loaʻa muscarinic a me nicotinic, e alakaʻi ana i nā hōʻailona e like me ka nāwaliwali o nā ʻiʻo, nā haʻalulu, a me ka pilikia hanu. Hiki i nā Anticholinesterases ke hoʻohuli i kēia mau hopena ma ka hoʻonui ʻana i nā pae acetylcholine a me ka hoʻokūkū me nā mea ʻawahia.
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ʻO Rapamycin mai Streptomyces hygroscopicus CAS: 53123-88-9
He hui kūlohelohe ʻo Rapamycin i hoʻokaʻawale ʻia mai ka bacteria Streptomyces hygroscopicus. Loaʻa iā ia kahi ākea o nā hana olaola a ua ʻike nui ʻia no kona mau waiwai immunosuppressive a me anti-cancer.
Ua ʻike mua ʻia ʻo rapamycin he mea antifungal, ua ʻike ʻia he mau waiwai immunosuppressive ikaika ko ka rapamycin, e lilo ai ia i mea waiwai nui i ka hoʻoili ʻana o nā kino e pale aku i ka hōʻole ʻana. Hana ia i kēia ma ke kāohi ʻana i ka hoʻoulu ʻana a me ka hoʻonui ʻana o nā T-cell, kahi ʻāpana koʻikoʻi o ka pane pale.
Eia kekahi, ua hōʻike ʻo rapamycin i nā hopena hoʻohiki i ka mālama ʻana i nā ʻano maʻi kanesa like ʻole. Hana ia ma ke kāohi ʻana i kahi protein i kapa ʻia ʻo mTOR (mammalian target of rapamycin), nona ke kuleana koʻikoʻi i ka ulu ʻana o nā cell a me ka mahele ʻana. Ma ka pale ʻana iā mTOR, kōkua ʻo rapamycin i ka kaohi ʻana i ka ulu ʻole o nā cell cancer.
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ʻAcylase mai ka ʻano Aspergillus CAS:9012-37-7
ʻO Acylase kahi enzyme i hana ʻia e nā ʻano like ʻole mai ka ʻano Aspergillus, me Aspergillus oryzae lāua ʻo Aspergillus niger. No ka ʻohana hydrolases kēia enzyme a pili i ka hydrolysis o nā hui acyl.
He kuleana koʻikoʻi ko nā Acylases i nā kaʻina hana biochemical like ʻole, ʻoi aku hoʻi i ka metabolism o nā hui organik. Hoʻoulu lākou i ka ʻoki ʻana o nā hui acyl mai kahi substrate, e hoʻohana pinepine ana i ka wai ma ke ʻano he co-reactant. Ua kapa ʻia kēia hopena enzymatic ʻo acyl hydrolysis.
Ua aʻo nui ʻia a hoʻohana ʻia nā Acylases mai ka ʻano Aspergillus i nā noi biotechnological. Ua hōʻike lākou i ka hiki ke hana i nā hui waiwai like ʻole e like me nā waikawa amino, nā antibiotics, a me nā mea lapaʻau ʻē aʻe.
